Free Radicals Scavenging and Antioxidant Activity of Vicia sojakii

نویسندگان

  • BAHMAN ESLAMI
  • SEYED FAZEL NABAVI
  • SEYED MOHAMMAD NABAVI
  • MOHAMMAD ALI EBRAHIMZADEH
چکیده

Some species of Vicia genus (Papilionaceae) are used in traditional medicine. In the present study, free radical scavenging and antioxidant activity of aerial parts of V. sojakii were investigated in six different models. IC50 for DPPH radical-scavenging activity was 440.4 ± 13.2 mg mL -1. It showed good nitric oxidescavenging activity between 0.2 and 1.6 mg ml-1. Extract showed very potent Fe2+ chelating ability. IC50 was 72 ± 2.8 mg mL-1. Extract exhibited low activity in linoleic acid peroxidation test. The total amount of phenolic compounds in extract was determined as gallic acid equivalents (47.8 ± 1.6 mg . g-1) and total flavonoid contents were calculated as quercetin equivalents (18.8 ± 0.47mg . g-1) from a calibration curve. Antioxidant activity may be attributed, at least in part, to the presence of phenols and flavonoids in the extract.

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تاریخ انتشار 2011